Lihua Bie-College of Informatics

Name

Lihua Bie

Title

Lecturer

Institute

College of Informatics, Huazhong Agricultural University

Address

No.1 Shizishan Street, Hongshan District, Wuhan 430070, China

Email

biebie@mail.hzau.edu.cn

Fax

Research Interest

High-performance computing, Molecular Simulation, Computer Architecture

Academic activities

Education and research experience

EDUCATION

Ph.D. Huazhong Agricultural University ,Wuhan, Hubei, P. R. China (2013-2018)

Doctor of Sciences, Bioinformatics Technology and Engineering

Advisor: Prof. Qiaoxia Yuan

Thesis: “Molecular Simulation of Methylation Regulation Mechanism in Interaction of bZIP Transcription Factors and DNA”

M.S. Huazhong University of Science and Technology, Wuhan,Hubei,P.R.China (2003-2008)

Master of Sciences, Computer Application

B.S. South-China University for Nationalities, Wuhan, Hubei, P. R. China (1997-2001)

Bachelor of Sciences, Computer Applied Technology

Grants (Government-funded)

Development and application of one-dimensional sliding model for regulating transcription factor specific recognition. Project ID: 2662020XXPY02, supported by the Fundamental Research Funds for the Central Universities. 2020.5-2023.4

Representative publications（*for corresponding authors, # for first authors）

1. Zhao, W.; Li, Q.; Huang, X. H.; Bie, L. H*.; Gao, J.*, Toward the Prediction of Multi-Spin State Charges of a Heme Model by Random Forest Regression. Front Chem 2020, 8：162.

2. Bie L#, Du L, Yuan Q, et al. How a single 5-methylation of cytosine regulates the recognition of C/EBPβ transcription factor: a molecular dynamic simulation study[J]. Journal of Molecular Modeling, 2018, 24(7):159.

3. Bie L#, Liu F, Li Y, et al. Spin crossover dynamics studies on the thermally activated molecular oxygen binding mechanism on a model copper complex.[J]. Physical Chemistry Chemical Physics , 2018, 20(23):15852.

4. Junxiang Gao Lihua Bie*，The Reform of Computer Organization Course Based on System Concept The 14th International Conference on Computer Science & Education (ICCSE 2019) August 19-21, 2019. Toronto, Canada

5. Bie Lihua#, Jiang Tianfa, Li Qian,Zhou Jin, Design and implementation of heuristic A-star algorithm on shortest path problem based on Hash table. Engineering Journal of Wuhan University,2016,49(6)

6. Gen Li, Yuan Quan, Xiaocong Wang, Rong Liu, Lihua Bie, Jun Gao* and Hong-Yu Zhang, Trinucleotide Base Pair Stacking Free Energy for Understanding TF-DNA Recognition and the Functions of SNPs. Frontiers in Chemistry, 2019. 6(666)

7. Huang Letian, Bie Lihua. Evaluation of homogeneous and heterogeneous multi-core System-on-Chip. Application of Electronic Technique. 2017.43(3):6-11

8.Shi Lijuan, Bie Lihua. An Analysis of the Obstacles and Causes of Flipping Classroom Implementation from the Differences between China and America Higher Agricultural Education.2017(1):125-127

Basic Information
Name	Lihua Bie		Title	Lecturer
Institute		College of Informatics, Huazhong Agricultural University
Address		No.1 Shizishan Street, Hongshan District, Wuhan 430070, China
Email		biebie@mail.hzau.edu.cn
Fax
Research Interest
High-performance computing, Molecular Simulation, Computer Architecture
Academic activities

Education and research experience
EDUCATION Ph.D. Huazhong Agricultural University ,Wuhan, Hubei, P. R. China (2013-2018) Doctor of Sciences, Bioinformatics Technology and Engineering Advisor: Prof. Qiaoxia Yuan Thesis: “Molecular Simulation of Methylation Regulation Mechanism in Interaction of bZIP Transcription Factors and DNA” M.S. Huazhong University of Science and Technology, Wuhan,Hubei,P.R.China (2003-2008) Master of Sciences, Computer Application B.S. South-China University for Nationalities, Wuhan, Hubei, P. R. China (1997-2001) Bachelor of Sciences, Computer Applied Technology
Grants (Government-funded)
Development and application of one-dimensional sliding model for regulating transcription factor specific recognition. Project ID: 2662020XXPY02, supported by the Fundamental Research Funds for the Central Universities. 2020.5-2023.4
Representative publications（*for corresponding authors, # for first authors）
1. Zhao, W.; Li, Q.; Huang, X. H.; Bie, L. H.; Gao, J., Toward the Prediction of Multi-Spin State Charges of a Heme Model by Random Forest Regression. Front Chem 2020, 8：162. 2. Bie L#, Du L, Yuan Q, et al. How a single 5-methylation of cytosine regulates the recognition of C/EBPβ transcription factor: a molecular dynamic simulation study[J]. Journal of Molecular Modeling, 2018, 24(7):159. 3. Bie L#, Liu F, Li Y, et al. Spin crossover dynamics studies on the thermally activated molecular oxygen binding mechanism on a model copper complex.[J]. Physical Chemistry Chemical Physics , 2018, 20(23):15852. 4. Junxiang Gao Lihua Bie，The Reform of Computer Organization Course Based on System Concept The 14th International Conference on Computer Science & Education (ICCSE 2019) August 19-21, 2019. Toronto, Canada 5. Bie Lihua#, Jiang Tianfa, Li Qian,Zhou Jin, Design and implementation of heuristic A-star algorithm on shortest path problem based on Hash table. Engineering Journal of Wuhan University,2016,49(6) 6. Gen Li, Yuan Quan, Xiaocong Wang, Rong Liu, Lihua Bie, Jun Gao and Hong-Yu Zhang, Trinucleotide Base Pair Stacking Free Energy for Understanding TF-DNA Recognition and the Functions of SNPs. Frontiers in Chemistry, 2019. 6(666) 7. Huang Letian, Bie Lihua. Evaluation of homogeneous and heterogeneous multi-core System-on-Chip. Application of Electronic Technique. 2017.43(3):6-11 8.Shi Lijuan, Bie Lihua. An Analysis of the Obstacles and Causes of Flipping Classroom Implementation from the Differences between China and America Higher Agricultural Education.2017(1):125-127