Xionghui Zhou-College of Informatics

Name

Xionghui Zhou

Title

Associate Professor

Institute

College of Informatics, Huazhong Agricultural University

Address

No.1 Shizishan Street, Hongshan District, Wuhan 430070, China

Email

zhouxionghui@mail.hzau.edu.cn

Fax

Research Interest

My research aera includes cancer systems biology and data mining. For several years, I have paied my attention to identify prognositc signatures and construct prognosis models for cancer patients, using network biology as tool. Recently, I am working on cancer early detection by using cell-free DNA fragmentation.

Academic activities

Member of Bioinformatics Division, Chinese Association for Artificial Intelligence

Member of China Computer Federation

Education and research experience

Education

2005.9 - 2009.7 Jinan University in Guangdong Computer Science, Bachelor

2009.9 - 2014.7 School of Computer, Wuhan University Computer Science, PhD

Experience

2014.7-2017.12 College of Informatics, Huazhong Agricultural University Lecturer

2018.1-present College of Informatics, Huazhong Agricultural University Associate Professor

2019.4 - present Cincinnati Children's Hospital Medical Center Research fellow

Grants (Government-funded)

Cancer hallmark mining based on DNA-methylation-interaction networks and its application in cancer-metastasis biomarker screening, the National Science Foundation of China, RMB 200K, 2017.01-2019.12

Cancer hallmark mining based on DNA-methylation-interaction networks and its application in cancer prognosis, the Natural Science Foundation of Hubei Province, RMB 50K, 2017.01-2018.12

Representative publications（*for corresponding authors, # for first authors）

1. Xiong-Hui Zhou, Xin-Yi Chu, Gang Xue, Jiang-Hui Xiong, Hong-Yu Zhang*.(2019) Identifying cancer prognostic modules by module network analysis. Bmc Bioinformatics 20 2019,20:85.

2. Ling-Hao Yu, Qin-Wei Huang, Xiong-Hui Zhou*. (2019) Identification of Cancer Hallmarks Based on the Gene Co-expression Networks of Seven Cancers. Frontiers in Genetics 2019,10:https://doi.org/10.3389/fgene.2019.00099.

3. Jianyong Wang, Lingling Chen, Xiong-Hui Zhou*. (2017) Identifying prognostic signature in ovarian cancer using DirGenerank. Oncotarget, 2017,doi: 10.18632/oncotarget.18189

4. Wei-Lin Hu, Xiong-Hui Zhou*. (2017) Identification of prognostic signature in cancer based on DNA methylation interaction network. Bmc Medical Genomics, 2017, 10(4):63.

5. Xiwen Xu#, Xiong-Hui Zhou#, Ruiru Wang, Wenlei Peng, Yue An, Lingling Chen*. (2016) Functional analysis of long intergenic non-coding RNAs in phosphate starved rice using competing endogenous RNA network, Scientific Reports 6, 2016, doi: 10.1038/srep20715

6. Xionghui Zhou, Juan Liu. (2014) A computational model to predict bone metastasis in breast cancer by integrating the dysregulated pathways. BMC Cancer 2014, 14:618.

7. Xionghui Zhou, Juan Liu, Wei Wang. (2014) Construction and investigation of breast-cancer-specific ceRNA network based on the mRNA and miRNA expression data. IET systems biology 8(3):pp.96-103.

8. Xionghui Zhou, Juan Liu, Xinhuo Ye, Wei Wang, Jianghui Xiong. (2013) Ensemble classifier based on context specific miRNA regulation modules: a new method for cancer outcome prediction. BMC Bioinformatics, 14(Suppl 12):S6.

9. Xionghui Zhou, Juan Liu, Jianghui Xiong. (2012) Predicting distant metastasis in breast cancer using ensemble classifier based on context specific miRNA regulation modules, 2012 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). pp. 1-6. (Regular paper).

Basic Information
Name	Xionghui Zhou		Title	Associate Professor
Institute		College of Informatics, Huazhong Agricultural University
Address		No.1 Shizishan Street, Hongshan District, Wuhan 430070, China
Email		zhouxionghui@mail.hzau.edu.cn
Fax
Research Interest
My research aera includes cancer systems biology and data mining. For several years, I have paied my attention to identify prognositc signatures and construct prognosis models for cancer patients, using network biology as tool. Recently, I am working on cancer early detection by using cell-free DNA fragmentation.
Academic activities
Member of Bioinformatics Division, Chinese Association for Artificial Intelligence Member of China Computer Federation
Education and research experience
Education 2005.9 - 2009.7 Jinan University in Guangdong Computer Science, Bachelor 2009.9 - 2014.7 School of Computer, Wuhan University Computer Science, PhD Experience 2014.7-2017.12 College of Informatics, Huazhong Agricultural University Lecturer 2018.1-present College of Informatics, Huazhong Agricultural University Associate Professor 2019.4 - present Cincinnati Children's Hospital Medical Center Research fellow
Grants (Government-funded)
Cancer hallmark mining based on DNA-methylation-interaction networks and its application in cancer-metastasis biomarker screening, the National Science Foundation of China, RMB 200K, 2017.01-2019.12 Cancer hallmark mining based on DNA-methylation-interaction networks and its application in cancer prognosis, the Natural Science Foundation of Hubei Province, RMB 50K, 2017.01-2018.12
Representative publications（*for corresponding authors, # for first authors）
1. Xiong-Hui Zhou, Xin-Yi Chu, Gang Xue, Jiang-Hui Xiong, Hong-Yu Zhang.(2019) Identifying cancer prognostic modules by module network analysis. Bmc Bioinformatics 20 2019,20:85. 2. Ling-Hao Yu, Qin-Wei Huang, Xiong-Hui Zhou. (2019) Identification of Cancer Hallmarks Based on the Gene Co-expression Networks of Seven Cancers. Frontiers in Genetics 2019,10:https://doi.org/10.3389/fgene.2019.00099. 3. Jianyong Wang, Lingling Chen, Xiong-Hui Zhou. (2017) Identifying prognostic signature in ovarian cancer using DirGenerank. Oncotarget, 2017,doi: 10.18632/oncotarget.18189 4. Wei-Lin Hu, Xiong-Hui Zhou. (2017) Identification of prognostic signature in cancer based on DNA methylation interaction network. Bmc Medical Genomics, 2017, 10(4):63. 5. Xiwen Xu#, Xiong-Hui Zhou*#, Ruiru Wang, Wenlei Peng, Yue An, Lingling Chen. (2016) Functional analysis of long intergenic non-coding RNAs in phosphate starved rice using competing endogenous RNA network, Scientific Reports 6, 2016, doi: 10.1038/srep20715 6. Xionghui Zhou, Juan Liu. (2014) A computational model to predict bone metastasis in breast cancer by integrating the dysregulated pathways. BMC Cancer 2014, 14:618. 7. Xionghui Zhou, Juan Liu, Wei Wang. (2014) Construction and investigation of breast-cancer-specific ceRNA network based on the mRNA and miRNA expression data. IET systems biology 8(3):pp.96-103. 8. Xionghui Zhou, Juan Liu, Xinhuo Ye, Wei Wang, Jianghui Xiong. (2013) Ensemble classifier based on context specific miRNA regulation modules: a new method for cancer outcome prediction. BMC Bioinformatics, 14(Suppl 12):S6. 9. Xionghui Zhou, Juan Liu, Jianghui Xiong. (2012) Predicting distant metastasis in breast cancer using ensemble classifier based on context specific miRNA regulation modules, 2012 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). pp. 1-6. (Regular paper).