XiaoHui Niu

Release time:May 27, 2020Edit:Browse times:

Personal Information

Basic Information

 Name

Xiaohui Niu

Title

Associate   Professor

Institute

College of Informatics, Huazhong Agricultural   University

Address

No.1   Shizishan Street, Hongshan District, Wuhan 430070, China

Email

niuxiaohi@mail.hzau.edu.cn

Fax

86+02787288509

Research Interest

·           My main   interests lie in two aspects: Integration analysis and mining of   biological big data for diseases and longitudinal data analysis.

1.         In biological   big data analysis, our group aims to find the hidden knowledge behind   biological big data. Our group integrates high-throughput and multi-omic   biological data from some public databases, such as TCGA, ENCODE and GTEx,   and develops some computational algorithms with machine learning and   statistical methods to solve some biological problems of diseases, especially   pan-cancers.

2.         In longitudinal   data analysis, our group aims to construct statistical models and perform statistical   inference with Generalized Estimation Equations to   analyse longitudinal data.

Academic activities

 

Education and research experience

05/2017-05/2018

Visiting     Scholar, Division of Biostatistics and     Bioinformatics,     University of California San Diego, California, USA

07/2014-present

Associate     Professor in Bioinformatics, College of Informatics, Huazhong Agricultural University,     Wuhan, China

01/2014-06/2014

Associate     Professor in Mathematics and Bioinformatics, College of Science, Huazhong     Agricultural University, Wuhan, China

01/2007-12/2013

Lecturer     in Mathematics, College of Science, Huazhong Agricultural University, Wuhan,     China

09/2008-07/2012

PhD     in Epidemiology and Health Statistics, Huazhong University of Science and     Technology, Wuhan, China

07/2004-12/2006

Assistant     Professor in Mathematics, College of Science, Huazhong Agricultural University, Wuhan,     China

09/2001-07/2004

Master     in Mathematics, Wuhan University, Wuhan, China

09/1997-07/2001

Bachelor     in Mathematics, Wuhan University, Wuhan, China

 

Grants (Government-funded)

01/2011-12/2013

·             National     Natural Science Foundation of China (NSFC) grant: “Researches and     applications of the survival analysis method based on support vector” (RMB     230K, 2013.01-2015.12)

 

Representative publications*for corresponding authors, # for first authors

[1] Xiaohui Niu#, Kaixuan Deng, Lifen Liu, Kun Yang, Xuehai Hu*. A   statistical framework for predicting critical regions of p53-dependent   enhancers. Briefings in Bioinformatics, doi: https://doi.org/10.1093/bib/bbaa053. (SCI, IF: 9.101)

[2] Wenqian Yang#, Yanbo   Yang#, Cecheng Zhao, Kun Yang, Dongyang Wang, Jiajun Yang, Xiaohui Niu*,   Jing Gong*.Animal-ImputeDB: a comprehensive database with   multiple animal reference panels for genotype imputation. Nucleic   Acids Research, gkz854, https://doi.org/10.1093/nar/gkz854. (SCIIF11.147)

[3] Xiaohui Niu#,   Kun Yang#, Ge Zhang, Zhiquan Yang and Xuehai Hu*. A Pretraining-Retraining   Strategy of Deep Learning Improves Cell-Specific Enhancer Predictions. Frontiers   in Genetics, 2020 Jan 8;10:1305. doi: 10.3389/fgene.2019.01305. (SCIIF3.517)

[4] Xiaohui Niu#, Xuehai   Hu*. Improved Prediction of DNA-Binding Proteins Using Chaos Game   Representation and Random Forest. Current Bioinformatics,   2016,11(2):156-163. (SCI, IF1.189)

[5]Xiaohui   Niu#, Xuehai   Hu*, Feng   Shi and Jingbo Xia. Predicting DNA binding proteins using support vector   machine with hybrid fractal features. Journal of Theoretical Biology,   2014, 343, 186-192.  (SCIIF2.496)

[6] Niu   Xiaohui#, Shi Feng, Hu Xuehai, Xia Jingbo, Li Nana*. Predicting the   protein solubility by integrating chaos games representation and entropy in information   theory. Expert Systems with Applications, 2014, 41(4):1672-1679.(SCI,   IF2.981)

[7] Xiaohui Niu#, Xuehai Hu*, Feng Shi and Jingbo   Xia. Predicting DNA binding proteins using support vector machine with hybrid   fractal features. Journal of   Theoretical Biology, 2014, 343, 186-192.  (SCIIF2.496)

[8] Niu Xiaohui#, Li Nana,Xia Jingbo,Chen Dingyan,Peng Yuehua,Xiao Yang , Wei Weiquan,Wang Dongming,Wang Zengzhen*. Using the concept of Chou's pseudo amino acid   composition to predict protein solubility: An approach with entropies in   information theory.  Journal of Theoretical Biology, 2013,332:211-217. (SCIIF2.303)







 

 

ICP 05008441 Address: No. 430070, Shizishan Street, Nanhu, Wuhan, Hubei Province
Telephone number: 027-87288509 recruitment and employment telephone number: 027-87286876 E Mail: Coi@mail. com. Hzau.edu.cn at coi-xinwen@mail. hzau.edu.cn

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