Bin-Guang Ma

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Personal Information

Basic Information



Bin-Guang Ma






College of Informatics, Huazhong Agricultural University 


1 Shizishan Jie, Hongshan Qu, Wuhan 430070, China




Research Interest

Physical Principles in Life; Computational and Engineering Methods for Biosystems

Academic activities

Member of the Hubei Bioinformatics Society (Since 2018)

Editorial Board Member of the Journal: Scientific Reports (Nature Publishing Group, Since 2015)

Judge for the iGEM-2013 competition (Asian Region, Hong-Kong, 2013)

Program Committee Member of the International Bioinformatics Workshop 2010 (IBW-2010, Wuhan, China, 2010)

Education and research experience

1997~2001: BSc (Physics): Hebei University of Technology

2001~2004: MSc (Biophysics): Tianjin University

2004~2007: PhD (Chemical Biology): Suzhou University

2007~2009: Post-Doctoral Researcher, Computational Biology Unit, Bergen Center for Computational Science, University of Bergen, Bergen 5008, Norway

2009~present: Huazhong Agricultural University

     Associate Professor, College of Life Science and Technology

     Professor, College of Informatics

Grants (Government-funded)

Systematic study on the regulation mechanisms of prokaryotic gene expression level in thermal adaptation (Grant number: 31100602), National Natural Science Foundation of China, 2012-2014.

Systematic study on the regulation mechanisms of thermal adaptation for bacterial 3D genomes (Grant number: 31570844), National Natural Science Foundation of China, 2016-2019.

Representative publications*for corresponding authors, # for first authors

1. Dong-Qing Sun, Liu Tian, Bin-Guang Ma*, Spatial organization of the transcriptional regulatory network of Saccharomyces cerevisiae, FEBS Lett. 2019, 593(8):876-884. 

2. Kang-Jian Hua, Bin-Guang Ma*, EVR: reconstruction of bacterial chromosome 3D structure models using error-vector resultant algorithm, BMC Genomics. 2019 15; 20(1):738. 

3. Yi Yang, Xiao-Pan Hu, Bin-Guang Ma*, Construction and simulation of the Bradyrhizobium diazoefficiens USDA110 metabolic network: a comparison between free-living and symbiotic states. Mol. BioSyst., 2017, 13: 607-620. 

4. Yi-Ming He, Bin-Guang Ma*, Abundance and Temperature Dependency of Protein-Protein Interaction Revealed by Interface Structure Analysis and Stability Evolution. Sci Rep. 2016 May 25; 6:26737. doi:10.1038/srep26737.

5. Bin-Guang Ma#, Alexander Goncearenco#, Igor N. Berezovsky* Thermophilic adaptation of protein complexes inferred from proteomic homology modeling. Structure (2010) 18, 819-828.

6. Bin-Guang Ma*, Ling-Ling Chen, Hong-Yu Zhang*. What determines protein folding type? An investigation of intrinsic structural properties and its implications for understanding folding mechanisms. Journal of Molecular Biology (2007) 370, 439-448. (Faculty of 1000 Biology)

7. Bin-Guang Ma*. How to describe genes: enlightenment from the quaternary number system. BioSystems (2007) 90, 20-27.

8. Bin-Guang Ma*, Jian-Xiu Guo, Hong-Yu Zhang*. Direct correlation between proteins' folding rates and their amino acid compositions: an ab initio folding rate prediction. Proteins: Structure, Function, and Bioinformatics (2006) 65, 362-372.



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