Lihua Bie

Release time:May 27, 2020Edit:Browse times:

Personal Information

Basic Information


Lihua Bie




College of Informatics, Huazhong Agricultural   University


No.1   Shizishan Street, Hongshan District, Wuhan 430070, China




Research Interest

High-performance computing, Molecular Simulation, Computer   Architecture

Academic activities


Education and research experience


Ph.D. Huazhong Agricultural University ,Wuhan, Hubei, P. R. China              (2013-2018)                   

Doctor of   Sciences,    Bioinformatics Technology and   Engineering                          

Advisor:  Prof.   Qiaoxia Yuan

Thesis:  “Molecular   Simulation of Methylation Regulation Mechanism in Interaction of bZIP Transcription   Factors and DNA”

M.S. Huazhong University of Science and Technology, Wuhan,Hubei,P.R.China   (2003-2008)

     Master of Sciences, Computer   Application

B.S. South-China University for Nationalities,   Wuhan, Hubei, P. R.   China        (1997-2001)

Bachelor of Sciences, Computer Applied Technology         


Grants (Government-funded)

Development and   application of one-dimensional sliding model for regulating transcription   factor specific recognition. Project ID: 2662020XXPY02, supported by the   Fundamental Research Funds for the Central Universities. 2020.5-2023.4


Representative publications*for corresponding authors, # for first authors

1. Zhao, W.;  Li, Q.;  Huang, X. H.;  Bie,   L. H*.; Gao, J.*, Toward the Prediction of Multi-Spin State Charges of a   Heme Model by Random Forest Regression. Front Chem 2020, 8162.

2. Bie L#, Du L, Yuan Q, et al. How a single 5-methylation of   cytosine regulates the recognition of C/EBPβ transcription factor: a molecular   dynamic simulation study[J]. Journal of Molecular Modeling, 2018,   24(7):159.

3. Bie L#, Liu F, Li Y, et al. Spin crossover dynamics studies   on the thermally activated molecular oxygen binding mechanism on a model   copper complex.[J]. Physical Chemistry Chemical Physics , 2018,   20(23):15852.

4. Junxiang Gao Lihua Bie*The Reform of Computer Organization Course Based on   System Concept  The 14th International Conference on Computer Science   & Education (ICCSE 2019) August 19-21, 2019. Toronto, Canada

5. Bie Lihua#, Jiang Tianfa, Li Qian,Zhou   Jin, Design and implementation of heuristic A-star algorithm on shortest path   problem based on Hash table. Engineering Journal of Wuhan   University,2016,49(6)

6.   Gen Li, Yuan Quan, Xiaocong Wang, Rong Liu, Lihua Bie, Jun Gao* and   Hong-Yu Zhang, Trinucleotide Base Pair Stacking Free Energy for Understanding   TF-DNA Recognition and the Functions of SNPs. Frontiers in Chemistry, 2019.   6(666)

7. Huang Letian, Bie Lihua.   Evaluation of homogeneous and heterogeneous multi-core System-on-Chip. Application   of Electronic Technique. 2017.43(3):6-11

8.Shi Lijuan, Bie Lihua. An   Analysis of the Obstacles and Causes of Flipping Classroom Implementation   from the Differences between China and America Higher Agricultural Education.2017(1):125-127



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